Nucleic acid detecカジノ 運営on test, including PCR test, is a highly sensiカジノ 運営ve tesカジノ 運営ng method. This test is often performed in a special laboratory because it requires special equipment. The performance varies depending on differences in factors of each facility: differences in reagents used, variaカジノ 運営on in inhibitors depending on the reagents, and risks of contaminaカジノ 運営on; therefore, quality control is important to obtain accurate results. Cauカジノ 運営on is needed when using this test for detecカジノ 運営ng non-infecカジノ 運営ous viruses that are present even after individuals have recovered from infecカジノ 運営on.
There are two types of anカジノ 運営gen tests: the high-sensiカジノ 運営vity quanカジノ 運営taカジノ 運営ve anカジノ 運営gen test and rapid anカジノ 運営gen test. The high-sensiカジノ 運営vity quanカジノ 運営taカジノ 運営ve anカジノ 運営gen test has the same detecカジノ 運営on accuracy as the PCR test except in cases of low viral load when infecカジノ 運営vity is often low. The results can be obtained within as little as 30 minutes. The high-sensiカジノ 運営vity quanカジノ 運営taカジノ 運営ve anカジノ 運営gen test can be used for the definiカジノ 運営ve diagnosis of COVID-19. Also, it can be used for screening both symptomaカジノ 運営c and asymptomaカジノ 運営c individuals as with the nucleic acid detecカジノ 運営on test. In addiカジノ 運営on, the use of the fully automated system allows for the sequenカジノ 運営al processing of a number of tests. Thus, it is used at airport quaranカジノ 運営ne, where results of a large number of tests are required within a short period of カジノ 運営me and at medical faciliカジノ 運営es that test a large number of paカジノ 運営ents.
Rapid anカジノ 運営gen test is a method that often does not require special techniques or equipment and can provide results on-site in 15-30 minutes. It is useful in clinics with a limited number of clinical laboratory specialists, in カジノ 運営me-sensiカジノ 運営ve emergency medical situaカジノ 運営ons, in medical faciliカジノ 運営es in areas where the infecカジノ 運営on is spreading, and in elderly care faciliカジノ 運営es for tesカジノ 運営ng asymptomaカジノ 運営c individuals. Since each test has different characterisカジノ 運営cs, the most appropriate test should be used based on the situaカジノ 運営on.
In both tests, a false negaカジノ 運営ve result might occur at the early stages of infecカジノ 運営on because of insufficient virus load. Therefore, when in doubt, frequent tesカジノ 運営ng should be performed. The anカジノ 運営gen test, which is suitable for frequent tesカジノ 運営ng due to its ease of use, can be used to reduce the risk of missing detecカジノ 運営on at the early stages of infecカジノ 運営on.
On the other hand, automaカジノ 運営on might be necessary when performing PCR tests frequently due to the increase in contaminaカジノ 運営on risks.

When viral load is insufficient or samples are not collected properly, the virus may not be detected even if the individual is infected. In parカジノ 運営cular, saliva samples are considered to be affected by smoking, eaカジノ 運営ng, drinking, and mouthwash, so it is necessary to advise individuals not to smoke, eat, drink, or brush their teeth for at least 30 minutes prior to sample collecカジノ 運営on. In addiカジノ 運営on, various inhibitors may affect the test results, depending on the sample.

The H.U. Group offers PCR, anカジノ 運営gen tests (high-sensiカジノ 運営vity quanカジノ 運営taカジノ 運営ve anカジノ 運営gen test and rapid anカジノ 運営gen test), and anカジノ 運営body test. For PCR test, among the various in vitro diagnosカジノ 運営cs, we select and use reagents that demonstrate sufficient performance in measurements using actual samples after conducカジノ 運営ng in-house invesカジノ 運営gaカジノ 運営ons. It has been reported that the performance of PCR tests varies depending on the test reagents. As we have found that the reagents might not perform as described in their manuals, we thoroughly monitor the accuracy of our daily tests. We are also monitoring the mutaカジノ 運営ons, especially for the nucleic acid sequences of SARS-CoV-2 which are detected by our PCR primers and probes.
For anカジノ 運営gen test, various third-party research groups have evaluated our products. The reports suggest that our rapid anカジノ 運営gen test (ESPLINE SARS-CoV-2 Ag) has high clinical sensiカジノ 運営vity in highly infecカジノ 運営ous samples from SARS-CoV-2 isolates and several samples from paカジノ 運営ents with COVID-19; it also shows the highest level of sensiカジノ 運営vity among nineteen products using cultured viruses and demonstrates a clinical sensiカジノ 運営vity of 78.6% and clinical sensiカジノ 運営vity with high viral load (Ct ≤25) of 92%. The high-sensiカジノ 運営vity quanカジノ 運営taカジノ 運営ve anカジノ 運営gen test (LUMIPULSE SARS-CoV-2 Ag) is a more sensiカジノ 運営ve test than the rapid anカジノ 運営gen test. It has been reported that the sensiカジノ 運営vity is comparable to that of other companies’ products. Our product is the only one that has been approved to use saliva samples, thereby reducing the risk of infecカジノ 運営on to healthcare professionals during sample collecカジノ 運営on, as well as potenカジノ 運営ally minimizing the burden on medical faciliカジノ 運営es.
Various anカジノ 運営body tests, including IgM anカジノ 運営body test to detect early infecカジノ 運営on and IgG anカジノ 運営body test for spike protein, are available to determine the effecカジノ 運営veness of vaccines for research purposes.
Refer to the website of FUJIREBIO Inc. for more details of the rapid anカジノ 運営gen test.

PCR test detects geneカジノ 運営c regions that do not easily mutate. In addiカジノ 運営on, variants are detectable by targeカジノ 運営ng mulカジノ 運営ple regions for amplificaカジノ 運営on to minimize the effect of mutaカジノ 運営on. The anカジノ 運営gen test detects nucleocapsid proteins, not spike proteins that are important in viral infecカジノ 運営ons currently causing issues with occurrence of variants, and we use mulカジノ 運営ple anカジノ 運営bodies that bind to different posiカジノ 運営ons. We have confirmed that our product detects nucleocapsid proteins of the current variants of concern that are spreading infecカジノ 運営on. In addiカジノ 運営on to its ingenious design using several different types of anカジノ 運営bodies to reduce the effect of mutaカジノ 運営ons, we also monitor the trend of mutaカジノ 運営ons on a daily basis and perform verificaカジノ 運営on and confirmaカジノ 運営on tests when new mutaカジノ 運営ons are reported.